Bionity.COM Newsletter No. 25/2010, 06/30/2010

New Products and Services

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Plug 'n Flow^TM: Pre-packed and ready-to-use biochromatography columns
Merck KGaA offers a convenient solution for high-performance, time and cost saving downstream purification processes: Plug 'n Flow^TM
Plug 'n Flow^TM are the convenient solution for high-performance, time and cost saving downstream purification processes from Merck KGaA. The ready-to-use columns feature the high-productivity tentacle ion exchange resins Fractogel® and Eshmuno^TM...

http://www.bionity.com/products/e/119350/

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Purospher® STAR HPLC and UHPLC columns
Columns based on high-purity silica for complex HPLC separations with excellent peak symmetry
Purospher® STAR RP-18 endcapped UHPLC columns are ideal for ultra-fast applications where resolution, sensitivity and sample throughput are crucial. They are the first choice for high-throughput screening and quality control analyses, process monitoring, method development, and LC/MS applications...

http://www.bionity.com/products/e/119286/

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Uninterrupted Data Flow Between LIMS and Lab Instruments
The Workflow Manager Controls the Lab
Manz Automation AG's Workflow Manager is a laboratory control software solution that takes over these tasks. Processes can be flexibly configured and linked to the sample data. The Workflow Manager controls the generated tasks across all connected instruments...

http://www.bionity.com/products/e/100385/

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Life Science loves Limsophy
New possibilities for the information management in your lab
AAC Infotray AG has developed a new product line which inspires people from Research and Analytics. Limsophy supports cross-departmental thinking and acting. "Philosophy of Limsophy" means integrated information management....

http://www.bionity.com/products/e/51678/

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Multi-Technology Microplate Reader with exceptional sensitivity
Dedicated optical paths (DOPS) ensure best available performance
The Mithras operates with a dedicated optical path system (DOPS): for each reading technology there is an optimum optical system guaranteeing high sensitivity and wide dynamic range for all measurements...

http://www.bionity.com/products/e/110106/

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Direct Inlet Probe (DIP) for Agilent 7000 MS/MS - fast MS analysis for complex samples
For fast screening methods, effectivity can be enhanced by connecting the DIP system with a special autosampler for liquid and/or solid samples....

http://www.bionity.com/products/e/108729/

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MVA 2.1 - A Supporting Tool in Method Validation
The Useful Software for an Efficient and Rational Validation of Analytical Methods
"Method Validation in Analytics - MVA" has been designed for the calculation of validation data based primarily on the guidelines of the International Conference on the Harmonization of Technical Requirements for the Registration of Pharmaceuticals for Human Use (ICH)...

http://www.bionity.com/products/e/58007/

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Biotech News

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Latest News from Biotechnology and Pharma from 06/23/2010 to 06/29/2010

Ablynx wins European Mediscience Award for the second year in a row
06/29/2010 - Ablynx has won the award for 'Best Technology' at the 2010 European Mediscience Awards for the second time in two years. The European Mediscience Awards Dinner celebrates the best in the sector and hi...
http://www.bionity.com/news/e/119480/

European CHMP concludes re-examination of ceftobiprole
06/29/2010 - Basilea Pharmaceutica Ltd. announces that following a request for re-examination from the Applicant Janssen-Cilag International NV, a Johnson & Johnson company, the European Committee for Medicinal Pr...
http://www.bionity.com/news/e/119421/

MorphoSys and Xencor Sign License and Collaboration Agreement for Clinical Antibody Program
06/29/2010 - MorphoSys AG and Xencor, Inc. announced the signing of a worldwide exclusive license and collaboration agreement for an antibody in Phase 1 clinical development. The agreement provides MorphoSys with...
http://www.bionity.com/news/e/119417/

Molecular Partners appoints Göran Ando as independent non executive board member
06/29/2010 - Molecular Partners AG announced the appointment of Dr Göran Ando as independent non-executive member of the board of directors.
Dr Ando brings considerable experience to the board of Molecular Part...
http://www.bionity.com/news/e/119477/

Basilea provides update on phase III program for the antifungal isavuconazole
06/29/2010 - Basilea Pharmaceutica Ltd. announced that its partner Astellas Pharma Inc.has initiated the formal process to allow continuation of patient recruitment into the phase III clinical studies of isavucona...
http://www.bionity.com/news/e/119420/

Gestational diabetes linked to serotonin and dietary protein
06/28/2010 - The cause of diabetes during pregnancy is directly controlled by serotonin, a chemical produced by the body and normally known as a neurotransmitter, and is influenced by the amount of protein in the ...
http://www.bionity.com/news/e/119412/

Pharming receives positive opinion from European Medicines Agency on Rhucin
Product name in Europe changed to Ruconest
06/28/2010 - Pharming Group NV announced that the European Medicines Agency's Committee for Medicinal Products for Human Use (CHMP) has adopted a positive opinion on Ruconest (Rhucin) for the treatment of acute an...
http://www.bionity.com/news/e/119366/

Amorfix and QED Bioscience announce agreement to develop novel monoclonal antibodies for cancer
06/28/2010 - Amorfix Life Sciences and QED Bioscience announced that they have entered into an agreement to develop high-affinity monoclonal antibodies against a number of targets for cancer. Under the agreement, ...
http://www.bionity.com/news/e/119416/

Large-scale genomic analysis of prostate cancer unveiled
06/28/2010 - A unique collaboration among physician-scientists at Memorial Sloan-Kettering Cancer Center (MSKCC) has yielded the most comprehensive genomic analysis of prostate cancer to date. "Genomic studies in ...
http://www.bionity.com/news/e/119415/

t2cure’s Cellular Therapeutic Receives Orphan Drug Designation from FDA, EMA Recommendation for Buerger’s Disease
06/28/2010 - t2cure GmbH announced that the FDA has granted orphan drug designation to t2c001 for the treatment of Buerger’s Disease. The Company also announced that in a concurrent application in Europe the EMA’s...
http://www.bionity.com/news/e/119363/

Supercomputer provides new insights into the vibrations of water
Biomolecular solutes perturb choreography
06/25/2010 - Using Terahertz spectroscopy, RUB-chemists recently detected the surprisingly long-ranged influence of solvated biomolecules on the "dance” of surrounding water molecules. With extensive simulations o...
http://www.bionity.com/news/e/119343/

Takeda to Expand Presence in Asia with Operations in South Korea
06/25/2010 - Takeda Pharmaceutical Company Limited announced it will establish a new commercial subsidiary in South Korea. Takeda aims to increase its global market coverage to approximately 90 percent by the end ...
http://www.bionity.com/news/e/119322/

Escalating Costs of Drug Development Drive the Pharmaceutical Companies to Tap Opportunities in Emerging Markets
06/25/2010 - The increased cost of drug development has impelled pharmaceutical companies to seek better opportunities in emerging markets to successfully expand and sell their products. Most pharmaceutical compan...
http://www.bionity.com/news/e/119362/

MediGene reports additional phase II results of EndoTAG-1 for the treatment of triple receptor-negative breast cancer
Clinical trial objective achieved - data confirm positive efficacy trend of EndoTAG-1 combination therapy
06/25/2010 - MediGene AG announces additional phase II clinical trial results of the drug candidate EndoTAGTM-1 for the treatment of triple receptor-negative breast cancer. The extensive data analysis of the three...
http://www.bionity.com/news/e/119359/

Crucell Announces Start of Universal RSV Vaccine Program
06/25/2010 - Crucell N.V. announced the start of a discovery program leading to the development and commercialization of a universal respiratory syncytial virus (RSV) vaccine. The RSV vaccine will be designed to p...
http://www.bionity.com/news/e/119358/

New details of an evolutionary mechanism
Scientists watch as E. coli bacteria evolve heat resistance under stress
06/24/2010 - Scientists in Munich report evidence that high concentrations of the molecular "chaperone" proteins GroEL and GroES – intracellular machines that can stabilize folding proteins under stress – play a c...
http://www.bionity.com/news/e/119317/

febit Announces Operational Restructuring
Strategic focus on partnerships with clinical researchers, diagnostic and pharma industry for its microRNA (miRNA) biomarker technology
06/24/2010 - febit announced a restructuring as a consequence of its strategic focus on blood-based microRNA biomarker discovery, febit’s major business development in 2009/2010, and on partnerships and intellectu...
http://www.bionity.com/news/e/119318/

Potential Cooperation Between Russia and India Regarding the Production of Pharmaceuticals Beneficial for Both Parties
Frost & Sullivan’s analysts comment on India’s plan to invest in the Russian pharmaceutical industry
06/24/2010 - India is ready to invest in the Russian pharmaceutical industry, including India-Russia joint ventures, as India's Commerce and Industry Minister, Anand Sharma, said during his visit to Russia last we...
http://www.bionity.com/news/e/119319/

Epigenomics AG Successfully Validates Lung Cancer Test in Clinical Trial
06/24/2010 - Epigenomics AG successfully completed the pivotal performance evaluation study for its Epi proLung BL Reflex Assay, a lung cancer diagnostic test. The test determines the DNA methylation status of th...
http://www.bionity.com/news/e/119320/

MorphoSys: First of up to Six Expected Clinical Phase 1 Milestones During 2010
06/24/2010 - MorphoSys AG announced that it will receive a clinical milestone payment from Centocor Ortho Biotech Inc. (formerly known as: Centocor, Inc.) in connection with the initiation of a phase 1 clinical t...
http://www.bionity.com/news/e/119296/

Molecular discovery suggests new strategy to fight cancer drug resistance
Prototype drug blocks MCL-1 protein that helps tumors survive treatment
06/23/2010 - Scientists at Dana-Farber Cancer Institute have found a way to disable a common protein that often thwarts chemotherapy treatment of several major forms of cancer. The researchers discovered, surprisi...
http://www.bionity.com/news/e/119234/

Cerenis to Present Clinical Proof-of-Concept Results for CER-627 program (niacin/aspirin combinations)
06/23/2010 - Cerenis Therapeutics SA announced it will present the results of two clinical proof-of-concept studies for its CER-627 program (niacin/aspirin combinations) at the 78th European Atherosclerosis Socie...
http://www.bionity.com/news/e/119262/

Quotient Bioresearch's New Radiochemistry Facility Fully Operational
06/23/2010 - Quotient Bioresearch announced that its new, state-of-the-art radiochemistry facility in Cardiff, UK is fully operational and that shipments of radiolabelled products have commenced. All staff have su...
http://www.bionity.com/news/e/119259/

Genetic Technologies appoints Lewis J. Stuart as General Manager of its New North American Molecular Diagnostics Business
06/23/2010 - Genetic Technologies Limited announced the appointment of Mr. Lewis Stuart as General Manager of its North American molecular diagnostics business. The new division is the result of the Company’s rec...
http://www.bionity.com/news/e/119258/

Flame retardant linked to altered thyroid hormone levels during pregnancy
06/23/2010 - Pregnant women with higher blood levels of a common flame retardant had altered thyroid hormone levels, a result that could have implications for fetal health, according to a new study led by research...
http://www.bionity.com/news/e/119235/

Catalogues and Brochures

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VITLAB - Competence in Labware
Extensive range of plastic and liquid handling products
VITLAB^® facilitates laboratory work with an extensive range of products for a wide variety of application areas like volume measurement, sample drawing, storage etc. See for yourself!...

http://www.bionity.com/catalogs/e/102507/

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Catalogue by Huber: High precision thermoregulation
Thermodynamics & Microelectronics - "it takes two to tango"
The catalogue shows over 500 thermostats and chillers over the temperature range of -120°C to 425°C. The model variety makes Scale-up easily possible and can be used on applications from research through Kilo and Pilot-Plant and into production...

http://www.bionity.com/catalogs/e/63847/

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